Large volume auto injectors are a hot topic, one that requires re-evaluating the traditional perception of patient comfort. Extended delivery times – once considered a barrier – are now acceptable for many patients, paving the way for a move from on-body drug delivery to an auto-injector based solution in many cases. Read our article on Developing Auto-Injectors: Designing for Small and Large Volume Drug Delivery
There is a clear tendency towards using device solutions offered by platform companies. However the complexity of the approval process for combination products is posing a significant challenge to the perceived ubiquity of platform devices. Also the flexibility required in supply chain and device features naturally adds to the costs and risks associated with such solutions. On the other hand developing a bespoke device is not always commercially viable for many new drugs, especially some orphan drugs or for smaller niche pharma companies. There is no perfect solution other than collaborative approaches and risk-mitigated compromises. Read our article on Platform vs Bespoke Drug Delivery Development: Strategic Choices for Effective Combination Products
Simulation and Modelling is a key tool for evaluating various aspects of combination products from design to performance, an approach that significantly reduces cost, time scale and risks to the programme. Read our article on Accelerating Medical Device Verification with Digital Twin Technology
Ash brings over 25 years of experience in leadership, board advisory roles and hands-on development within the health tech and medical device sectors. He has successfully guided numerous national and international companies through the complete product lifecycle from ideation to full-scale commercialisation and scale-up.
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